Chemical Name:    L-homophenylalanine

Synonyms:            L-2-amino-4-phenylbutyric acid 

                             L-4-phenyl-2-aminobutanoic acid

Chemical Formula:    C10H13NO2

Structural Formula:

Molecular Weight:    179.22

CAS Number:           943-73-7

Description:              White crystal powder

L-homophenylalanine (called LHPA for short) is a chiral unnatural a-amino acid. It is widely used in the synthesis of pharmaceuticals and pesticides.

It is an important intermediate for the synthesis of ACE-inhibitors (angiotension-converting enzyme inhibitors) such as Lisinopril to treat hypertension (high blood pressure and heart failure) and CHF(Congestive Heart Failure). It may also be used for the synthesis of NEPA [(S,S)-N-(1-Ethoxycarbonyl-3-phenylpropyl)alanine],which is a key intermediate to produce ACE-inhibitors such as Enalapril, Delapril, Quinapril, Ramipril etc..